Help, we’re drowning in wireframing apps!

Back in the 1990s, when wireframing was a niche activity, you were pretty much limited to Visio or Illustrator. Nowadays there are a huge number of alternatives. If you want an online app, you can choose from Balsamiq, Just in Mind, Jumpchart, iPlots, iZotz, HotGloo, Connect-A-Sketch, ForeUI, Pidoco, Simulify, Mockup screens, Mocklinr, Wireframe sketcher, Gliffy, Lovely Charts, Project Draw, Creately, Napkee among zillions of others. Offline the situation is equally messy, we’ve got Axure, Omnigraffle, Visio, Sketchflow, iRise, Inkscape, Illustrator, Fireworks, Indesign, Pencil, Denim, Serena, Qmockup, Flairbuilder, Photopro, Caretta Studio, and there’s also reams of GUI builder apps if you’re designing desktop apps. The list just goes on and on. How do you know which ones to use and which to avoid?

Has anyone actually tried them all and created an über comparison table? Not as far as I can tell. Instead I’m sort of hoping for some kind of K-T event to kill of all of the weaker ones. Not sure how that would work, though. Any ideas?

Amendment: post has been repeatedly edited to include additional tools.

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